Career
Work alongside a team led by scientists in the life sciences, taking on cancer and viral disease with AI, DNA-encoded library screening and medicinal chemistry.
Meet our peopleBiology Research Scientist
View job responsibilities and requirementsPhD or postdocIn vitro assaysBiophysicsSARRun in vitro potency and selectivity assays for compounds, investigate mechanisms of action, perform in vitro biophysical experiments and support SAR studies in the chemistry department;Responsibilities
- Run in vitro potency and selectivity assays for compounds, investigate mechanisms of action, perform in vitro biophysical experiments and support SAR studies in the chemistry department;
- Design experimental plans from literature research, run screening assays, process and review data, analyse results, and propose solutions and next steps;
- Track new technologies and tools, and continuously improve the in vitro bioactivity and biophysics platforms.
Requirements
- PhD or postdoctoral experience in biochemistry, biophysics, pharmacology, biology or a related field.
Send your CV by email · Subject: "Application: Biology Research Scientist"
Medicinal Chemistry Scientist
View job responsibilities and requirementsPhD or postdocSmall-molecule synthesisLead optimisationPK propertiesLead a team in designing and synthesising small-molecule inhibitors, optimising lead compounds, studying structure-activity relationships and improving PK properties, and support in vitro and in vivo efficacy testing as well as safety and developability assessment of candidates;Responsibilities
- Lead a team in designing and synthesising small-molecule inhibitors, optimising lead compounds, studying structure-activity relationships and improving PK properties, and support in vitro and in vivo efficacy testing as well as safety and developability assessment of candidates;
- Track, collect and organise data on relevant targets, and support target nomination and project evaluation.
Requirements
- PhD or postdoctoral experience in organic chemistry, medicinal chemistry or a related field.
Send your CV by email · Subject: "Application: Medicinal Chemistry Scientist"
AI Drug Design Scientist
View job responsibilities and requirementsPhD or postdocCADDGenerative modelsHigh-performance computingApply the company's in-house AI algorithms to concrete drug design projects, working with medicinal chemists on lead discovery and optimisation;Responsibilities
- Apply the company's in-house AI algorithms to concrete drug design projects, working with medicinal chemists on lead discovery and optimisation;
- Help build a high-performance computing platform for drug design, evaluate and improve computational methods, and optimise the computational workflow.
Requirements
- PhD or postdoctoral experience in computational chemistry, computational biology or a related field;
- Substantial CADD or medicinal chemistry experience, with some understanding of deep learning, especially generative models.
Send your CV by email · Subject: "Application: AI Drug Design Scientist"
Senior Research Scientist, Drug Screening
View job responsibilities and requirementsPhD or postdocTarget researchProtein expressionActivity assaysResearch drug targets and take part in evaluating and nominating new targets;Responsibilities
- Research drug targets and take part in evaluating and nominating new targets;
- Carry out recombinant expression and purification of target proteins;
- Establish in vitro activity assays for target proteins and run activity testing;
- Run drug screening and activity testing against target proteins.
Requirements
- PhD or postdoctoral experience in molecular biology, biochemistry, structural biology or a related field;
- Familiar with cell culture, molecular cloning and similar laboratory techniques; experience in recombinant protein expression and purification is preferred;
- Able to read English literature comfortably and write English research reports;
- Responsible, with good teamwork skills.
Send your CV by email · Subject: "Application: Senior Research Scientist, Drug Screening"
Project Management Manager
View job responsibilities and requirementsMaster's or abovePreclinical programme managementCMCRegulatory filingsOwn the company's project management system — its policies, standards and processes — and supervise their execution;Responsibilities
- Own the company's project management system — its policies, standards and processes — and supervise their execution;
- Manage preclinical drug programmes: define objectives, build plans, coordinate the functions involved, keep priorities clear and drive projects to schedule;
- Lead CMC work across synthesis, analytical development, formulation, regulatory affairs and quality control;
- Ensure R&D processes follow drug filing requirements and meet compliance audit needs;
- Organise the writing and submission of new drug applications, and track domestic and international filing regulations;
- Facilitate cross-functional communication against the project plan, monitor progress and quality, and propose changes where needed.
Requirements
- Master's degree or above in medicinal chemistry, organic synthesis, pharmaceutical analysis, formulation or a related field;
- 5+ years of project management in innovative drug R&D, covering preclinical and clinical stages, with familiarity with stage-gate technology transfer;
- Experience managing or supervising several projects at once; experience developing or using commercial project management tools is preferred;
- Strong written and spoken Chinese and English; able to drive projects quickly by priority, facilitate collaboration among parties and solve problems in line with company strategy;
- Familiar with domestic and international drug registration regulations and guidelines; experience in clinical trial standards, design and operations is preferred.
Send your CV by email · Subject: "Application: Project Management Manager"
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How to apply: send your resume and cover letter to the email address indicated for the role.